Gene information
Official symbol MECOM
Official full name MDS1 and EVI1 complex locus
Gene type protein-coding gene
Chromosome3q26.2
Alias symbolMDS1-EVI1; PRDM3; KMT8E
Previous symbolMDS1; EVI1
Gene familyZinc fingers C2H2-type; Lysine methyltransferases; PR/SET domain family
Resources
Entrez Gene 2122
HGNC HGNC:3498
Ensembl ENSG00000085276
Vega OTTHUMG00000158596
UCSC uc003ffi.3
GO terms: 11 records
GO Description Category LogP Number of genes Detail
GO:0001216 DNA-binding transcription activator activity GO Molecular Functions -9.83829980 29 More
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific GO Molecular Functions -9.92639238 29 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043409 negative regulation of MAPK cascade GO Biological Processes -13.5471736 35 More
GO:0046328 regulation of JNK cascade GO Biological Processes -6.26985667 21 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05220 Chronic myeloid leukemia KEGG Pathway -2.89550682 10 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg10953508 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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